Resources

Dominion Diagnostics is committed to providing clinical tools and resources to support healthcare education. Here you’ll find links to clinically relevant podcasts, videos, technical papers, research and more.

Urine Drug Monitoring: Opioids

Monitoring patient usage of scheduled controlled substances is a major concern and responsibility of prescribing clinicians.  This handbook collects the most effective techniques for monitoring pharmacotherapy, with an emphasis on opioids...

Unchain Your Brain: 10 Steps to Breaking the Addictions that Steal Your Life

Unchain Your Brain: 10 Steps to Breaking the Addictions that Steal Your Life is a practical, easy-to-follow, step-by-step program that shows you how to boost your brain so you can kick your bad habits.  In this book, you will discover:...

Understanding Elimination Patterns with Creatinine Adjusted Drug Values

Creatinine is a product of muscle contraction. Because it is produced from within and released into body fluids at a relatively constant rate, the level of creatinine in urine may be used as an indication of body hydration. Since measured...

Genetic Addiction Risk Score (GARS): Molecular Neurogenetic Evidence for Predisposition to Reward Deficiency Syndrome (RDS)

We have published extensively on the neurogenetics of brain reward systems with reference to the genes related to dopaminergic function in particular. In 1996, we coined "Reward Deficiency Syndrome" (RDS), to portray behaviors found to...

Withdrawal from Buprenorphine/Naloxone and Maintenance with a Natural Dopaminergic Agonist: A Cautionary Note

While numerous studies support the efficacy of methadone and buprenorphine for the stabilization and maintenance of opioid dependence, clinically significant opioid withdrawal symptoms occur upon tapering and cessation of dosage. We...

Neurogenetic Impairments of Brain Reward Circuitry Links to Reward Deficiency Syndrome (RDS): Potential Nutrigenomic Induced Dopaminergic Activation

Work from our laboratory in both in-patient and outpatient facilities utilizing the Comprehensive Analysis of Reported Drugs (CARD)™ found a significant lack of compliance to prescribed treatment medications and a lack of abstinence from...

Urinary Analytes for Patients Taking Opiate-Based Medications

Quantitative urine analysis by UPLC-MS/MS has the capability of detecting analytes of frequently prescribed opiate-based medications; codeine, morphine, hydrocodone, hydromorphone, oxycodone, and oxymorphone. Codeine Approximately 5% to 15...

Urinary Analytes for Patients Taking Benzodiazepine Medications

Quantitative urine analysis by UPLC-MS/MS has the capability of detecting analytes of frequently prescribed benzodiazepine medications:  alprazolam, chlordiazepoxide, clonazepam, clorazepate, diazepam, flurazepam, lorazepam, oxazepam,...

Systematic Evaluation of “Compliance” to Prescribed Treatment Medications and “Abstinence” from Psychoactive Drug Abuse in Chemical Dependence Programs: Data from the Comprehensive Analysis of Reported Drugs

This is the first quantitative analysis of data from urine drug tests for compliance to treatment medications and abstinence from drug abuse across “levels of care” in six eastern states of America. Comprehensive Analysis of Reported Drugs...

Quantitative Electroencephalography Analysis (qEEG) of Neuro-Electro- Adaptive Therapy 12™ [NEAT12] Up-Regulates Cortical Potentials in an Alcoholic during Protracted Abstinence: Putative Anti-Craving Implications

Introduction: Cranial electrotherapy stimulation (CES) is a noninvasive therapy that has been used for decades in the United States to treat anxiety, depression, and insomnia in the general  population. The effectiveness of CES has been...

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